lower price PF06463922(1454846-35-5) supply CAS NO.1454846-35-5

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Product Details

Keywords

PF06463922
1454846-35-5
PF-06463922

Quick Details

ProName: lower price PF06463922(1454846-35-5) s...
CasNo: 1454846-35-5
Molecular Formula: C21H19FN6O2
Appearance: white powder
Application: used for research
DeliveryTime: Within 3 days after receive payment
PackAge: Sealed aluminum foil package
ProductionCapacity: Metric Ton/Day
Purity: 99
Storage: cool and dry place
Transportation: By courier/ By air
LimitNum: 1 Gram
Related Substances: Not available
Residue on Ignition: Not available
Heavy Metal: Not available
Valid Period: Not available

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Details

Biological Activity

Description	PF-06463922 is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. Phase 1.

Chemical Information

Molecular Weight (MW)	406.41
Formula	C21H19FN6O2
CAS No.	1454846-35-5

Storage	3 years -20℃powder
Storage	6 months-80℃in solvent
Synonyms	PF-06463922

Solubility (25°C)*	In vitro	DMSO	81 mg/mL (199.3 mM)
		Ethanol	81 mg/mL warmed (199.3 mM)
		Water	<1 mg/mL (<1 mM)
<1 mg/ml means slightly soluble or insoluble.

Chemical Name	(10R)-7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile