- Product Details
Keywords
- Fludarabine
- 21679-14-1
- C10H12FN5O4
Quick Details
- ProName: lower price Fludarabine(21679-14-1)su...
- CasNo: 21679-14-1
- Molecular Formula: C10H12FN5O4
- Appearance: white powder
- Application: used for research
- DeliveryTime: 3 days
- PackAge: aluminum foil bag
- Port: shenzhen
- ProductionCapacity: 1 Metric Ton/Day
- Purity: 99%min
- Storage: Store in cool, dry, ventilated place
- Transportation: by sea or by air
- LimitNum: 1 Gram
- Related Substances: N/A
- Residue on Ignition: N/A
- Heavy Metal: N/A
- Valid Period: one year
- N/A: N/A
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Fludarabine Basic information Product Name: Fludarabine Synonyms: 2-Fluoroadeninearabinoside;9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin;9-beta-d-arabinofuranosyl-2-fluoro-adenin;f-ara-a;6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE;9-bata-d-arabinofuranosyl-2-fluoroadenine;9-BETA-D-ARABINOFURANOSYL-2-FLUORO-9H-PURIN-6-AMINE;9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE CAS: 21679-14-1 MF: C10H12FN5O4 MW: 285.23 EINECS: 244-525-5 Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API Mol File: 21679-14-1.mol Fludarabine Chemical Properties mp 265-268°C storage temp. 2-8°C solubility DMF: 20 mg/mL, clear, faintly yellow Merck 13,4152 CAS DataBase Reference 21679-14-1(CAS DataBase Reference) Safety Information Risk Statements 23/24/25-36/37/38-39/23/24/25-39 Safety Statements 26-36/37-45 WGK Germany 3 RTECS AU6207000 F 10 Hazardous Substances Data 21679-14-1(Hazardous Substances Data) Fludarabine Usage Synthesis Chemical Properties White Solid Usage Used as an antineoplastic Usage A STAT-1 activation inhibita DNA synthesis inhibitor. Biological Activity Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) triggers apoptosis through increasing Bax decreasing Bid, XIAP survivin expression. Displays anticancer activity against hematological malignancies in vivo . Fludarabine Preparation Products Raw materials Raw materials Acetic anhydride-->Fluoroboric acid-->Boron trichloride -->2,4,5,6-TETRAAMINOPYRIMIDINE-->2,6-Diaminopurine-->DIACETAMIDE